| HMG-CoA | |
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(9R,21S)-1-[(2R,3S,4R,5R)-5- (6-amino-9H-purin-9-yl)-4-hydroxy- 3-(phosphonooxy)tetrahydrofuran-2-yl]- 3,5,9,21-tetrahydroxy-8,8,21-trimethyl- 10,14,19-trioxo-2,4,6-trioxa-18-thia- 11,15-diaza-3,5-diphosphatricosan-23- oic acid 3,5-dioxide |
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| Identifiers | |
| CAS number | 1553-55-5 |
| PubChem | 445127 |
| ChemSpider | 392859 |
| MeSH | HMG-CoA |
| ChEBI | CHEBI:61659 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C27H44N7O20P3S |
| Molar mass | 911.661 g/mol |
| (verify) (what is: /?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
HMG-CoA (or 3-hydroxy-3-methylglutaryl-coenzyme A) is an intermediate in the mevalonate and ketogenesis pathways. It is formed from acetyl CoA and acetoacetyl CoA by HMG-CoA synthase.
It is also an intermediate in the metabolism of leucine. Its immediate precursor is 3-methylglutaconyl CoA.
HMG-CoA reductase converts it into mevalonic acid.
HMG-CoA lyase breaks it into acetyl CoA and acetoacetate.
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